JAM掲載論文検索
| Japanese Acupuncture and Moxibustion (Online) |
| 2005; 1: 9-15 |
| A Proposal for a Simple and Useful Research Design for Evaluating the Efficacy of Acupuncture: Multiple, Randomized n-of-1 Trials |
| KAWAKITA Kenji 1), SUZUKI Masao 2), NAMURA Kenji 2), TANZAWA Shouhachi 1) |
| 1) Research Department of Japan Society of Acupuncture and Moxibustion 2) Department of Internal Medicine, Meiji University of Oriental Medicine |
 |
| Fig. 3 A block diagram of the protocol of multiple randomized n-of-1 trials |
| Patients are randomly allocated to each group then the effect of acupuncture or control intervention in each patient is evaluated by an n-of-1 trial (the randomization test can be used). Incidences of positive or negative results are analyzed statistically. (using chi-square test ). In this case, chi square=6.3349 and p=0.0117. However, small samples require Yates' continuity correction, with which the results become, chi-square=4.063, p=0.0438. This result indicates the external validity of n-of-1 trials. |