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Japanese Acupuncture and Moxibustion (Online)
2011; 1: 22-30
Therapeutic Effect of Moxibustion on Collagen-induced Arthritis in Mice by Induction of Regulatory T Cells
MIMURA Naomi1,2), KOGURE Morihiro1), IKEMOTO Hideshi1), SUNAGAWA Masataka1), ISHIKAWA Shintaro1), FUKUSHIMA Masaya1), ISHINO Shogo1), HISAMITSU Tadashi1)
1) Department of Physiology, School of Medicine, Showa University, Tokyo, Japan
2) Shinjuku Vocational School of Acupuncture and Judo Therapy, Tokyo, Japan
Figure 3. The therapeutic effects of moxibustion on CIA development.
A, The incidence of CIA is indicated as the percentage of mice developing a clinical arthritis score of more than 1. B, The clinical arthritis scores were evaluated using a scoring system as follows: 0 = normal, 1 = erythema and swelling of one digit, 2 = erythema and swelling of more than two digits or mild erythema and swelling of the entire paw, 3 = progressively more severe erythema and swelling of the entire paw, 4 = severe swelling and erythema with lack of flexibility. The open circles indicate the no-treated CIA mice (n=35) and the closed circles indicate the moxibustion-treated CIA mice (n=32). The data represent the mean ア・SEM. Significant differences from the no-treated CIA mice are indicated with *p<0.05 and **p<0.01.

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