Japanese Acupuncture and Moxibustion (Online)
2011; 1: 22-30
Therapeutic Effect of Moxibustion on Collagen-induced Arthritis in Mice by Induction of Regulatory T Cells
MIMURA Naomi1,2), KOGURE Morihiro1), IKEMOTO Hideshi1), SUNAGAWA Masataka1), ISHIKAWA Shintaro1), FUKUSHIMA Masaya1), ISHINO Shogo1), HISAMITSU Tadashi1)
1) Department of Physiology, School of Medicine, Showa University, Tokyo, Japan
2) Shinjuku Vocational School of Acupuncture and Judo Therapy, Tokyo, Japan
Figure 4. The effects of moxibustion on the population of CD 4+CD 25+ T cells in CD 4+ T cells in the peripheral blood (A), spleen (B) and inguinal lymph nodes (C).
The white bars indicate the no-treated normal mice or the no-treated CIA mice. The black bars indicate the moxibustion-treated normal mice or the moxibustion-treated CIA mice. The data represent the mean ア・SEM of 5 mice (A and B) or 10 mice (C) per group. Significant differences are indicated with *p<0.05, **p<0.01 and ***p<0.001, respectively. D, A flow cytometric image of the whole CD 4+CD 25+ T cells (left) was created on CellQuest software. A histogram (right) was created to obtain the percentage of CD 4+CD 25+ T cells in CD 4+ T cells. This is the representative data of peripheral blood taken from a no-treated CIA mouse (blank) and a moxibustion-treated CIA mouse (gray).

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